June 2022: Our light-sheet PF-OCE paper published in Nature Communications

This paper presents the use of light-sheet photonic force for parallel mechanical loading, and demonstrates high-throughput quantitative 3D micromechanical imaging.  We quantify the micromechanical heterogeneity of fibrous collagen matrices and perform live-cell imaging of cell-mediated ECM micromechanical dynamics.  Our 4D imaging of micromechanical dynamics of cell-mediated ECM deformations enabled observations that, to our knowledge, have never been reported by other techniques. For further information check our paper Light-sheet photonic force optical coherence elastography for high-throughput quantitative 3D micromechanical imaging.

Leave a Reply

Your email address will not be published. Required fields are marked *