We have been awarded a grant through the NIH BRAIN Initiative to integrate hardware and computational adaptive optics for imaging deeper into the living mouse brain.
This research will be conducted in collaboration with the Xu Lab (Cornell, Applied and Engineering Physics). Through enhanced aberration sensing and correction, we hope to enable the imaging of neural activity well into the hippocampus, potentially reaching the dentate gyrus layers (> 1.5 mm) where newly generated neurons are continuously being incorporated into networks.