June 2018: Siyang’s ‘hybrid adaptive optics’ paper published in Biomedical Optics Express!

In this paper we introduce a new ‘hybrid adaptive optics’ (hyAO) approach that synergistically combines hardware adaptive optics (HAO) and computational adaptive optics (CAO).  We show that hyAO can significantly increase the throughput of large-volume, optical coherence microscopy, and use it to image cell population dynamics over a 1mm × 1mm × 1mm field-of-view with 2 μm isotropic spatial resolution and 3-minute temporal resolution.

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