March 2019: Jeff’s TF-OCM paper published in Scientific Reports!

In this paper we demonstrate quantitative TF-OCM for reconstruction of 3D cell forces with minute-scale temporal resolution. Due to the ability of computational OCM to perform large-scale volumetric and label-free imaging in scattering media, TF-OCM may prove advantageous for the study of the force dynamics of large cell collectives in the burgeoning field of mechanobiology.

August 2018: The group welcomes new postdoc Yuechuan Lin

Lin obtained his B.Sc from Nankai University in 2013 and his Ph.D from The Hong Kong Polytechnic University in 2018, under the supervision of Prof. Wei Jin. During his Ph.D studies, he explored novel ultra-sensitive optical spectroscopy techniques, especially the microstructure-enhanced photothermal spectroscopy in photonic crystal fibres. His current research focuses on new approaches for photonic force optical coherence elastography, and quantitative investigations of mechanical properties for stem cell mechanobiology research.

June 2018: Siyang’s ‘hybrid adaptive optics’ paper published in Biomedical Optics Express!

In this paper we introduce a new ‘hybrid adaptive optics’ (hyAO) approach that synergistically combines hardware adaptive optics (HAO) and computational adaptive optics (CAO).  We show that hyAO can significantly increase the throughput of large-volume, optical coherence microscopy, and use it to image cell population dynamics over a 1mm × 1mm × 1mm field-of-view with 2 μm isotropic spatial resolution and 3-minute temporal resolution.